Patient safety has been Aguettant's priority since its creation. Our teams are focused on the development of a range of health products adapted to the challenges of daily medical practice with, in particular, ready-to-administer injectable medicines (pre-filled syringes) to make a safer environment.

Serving healthcare

professionals

See the testimony of Professor William Harrop-Griffiths, Consultant Anaesthetist, Imperial College Healthcare NHS Trust, London, United Kingdom

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EBA European Board of Anaesthesiology
EAHP European Association of Hospital Pharmacists
SFAR French Society of Anesthesia and Resuscitation
EBA European Board of Anaesthesiology

« Recommends that pre-filled syringes should be used wherever possible. » (1)

EAHP European Association of Hospital Pharmacists

recommends, « minimise bedside preparation of intravenous medications and replace with procured and centrally prepared « ready-to-administer » or « ready-to-use » medications wherever possible. » (2)

SFAR French Society of Anesthesia and Resuscitation

« Experts suggest that anaesthetists preferentially use pre-filled syringes for occasional use medications when they have them, rather than preparing these medications in advance in conventional syringes, to reduce the environmental impact of general anaesthesia » (translated) (3)

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Description

Our polypropylene syringes are delivered pre-filled and ready-to-use in sterile packaging.

We strive to design innovative, ready-to-administer solutions to prevent medication errors, especially in emergency situations. (4)

Thirteen drugs for injection in pre-filled syringes already exist and others are under development.

Technical diagram of an Aguettant syringe and its packaging. The syringe consists of a protective cap with a tamper-evident label, a Luer-compatible connector, and a polypropylene barrel with dual graduations and an ISO 26825 label. At the rear is the pre-assembled plunger and its cap. The device is presented on top of its sterile Tyvek blister pack with terminal sterilisation.
Technical diagram of an Aguettant syringe and its packaging. The syringe consists of a protective cap fitted with a tamper-evident label, a Luer-compatible connector, a polypropylene barrel with dual graduations, and a label compliant with ISO 26825. At the rear is the pre-assembled plunger and its stopper. The device is shown above its sterile Tyvek blister pack with terminal sterilisation.
See the text description of the syringe diagram

Ready to Administer

at a Glance

Reduction of

medication errors

FLECHE

“A significant number of the potential human factor error steps in preparation of injectable medicines can be completely eliminated when using prefilled prelabelled syringes." (4)

It has been proven that "Medication errors were 17 times less likely when prefilled syringes were used". (5)

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Reduction of

microbial contamination

FLECHE

"Prefilled syringes have zero contamination as against 6% for manually prepared syringes." (4) (6)

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Reduced administration

delays

FLECHE

When fast administration is essential, hand-preparing drugs at the bedside can result in delays in treatment. (5)

Ready-to-use pre-filled syringes eliminate preparation time, making them a suitable solution for emergency situations.

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Reduced risks of injuries

for healthcare professionals

FLECHE

Use of pre-filled syringes eliminates needle-stick and cut injuries when opening glass ampoules. (7)

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Waste and

waste reduction

FLECHE

Up to 86% of injectable drugs prepared in advance in the operating theater and intensive care are discarded at the end of the day. (8)

Considering all components used in the preparation steps of ampoules (syringe, drug, needle, pad, diluent...etc), pre-filled syringes could reduce your overall plastic use and the amount of waste you send to incinerators.

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Time saving

for caregivers

FLECHE
The preparation time for the syringes is time-consuming for healthcare staff.

Opting for pre-filled syringes means spending more time with patients.
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(1) EBA European Board of Anaesthesiology Recommendations for Safe Medication Practice 2015
(2) EAHP Report 2023 GIG Special Interest Group for the investigation of medication errors in intensive care units
(3) SFAR Guidelines for Reducing the environmental impact of general anaesthesia 2022
(4) Preckel B et al. Ten years of the Helsinki Declaration on patient safety in anaesthesiology. Eur J Anaesthesiol 2020; 37:521–610
(5) Adapa RM, Mani V, Murray LJ, Degnan BA, Ercole A, Cadman B, Williams CE, Gupta AK, Wheeler DW. Errors during the preparation of drug infusions: a randomized controlled trial. Br J Anaesth. 2012 Nov;109(5):729-34. doi: 10.1093/bja/aes257. Epub 2012 Jul 31. PMID: 22850220.
(6) Gargiulo DA, Mitchell SJ, Sheridan J, et al. Microbiological contamination of drugs during their administration for anesthesia in the Operating Room. Anesthesiology 2016; 124; 785-794.
(7) European Agency for Safety & Health at Work. https://osha.europa.eu/en/legislation/directives/council-directive-2010-32-eu-prevention-from-sharp-injuries-in-the-hospital-and-healthcare-sector
(8) Barbariol F, Deana C, Lucchese F, Cataldi G, Bassi F, Bove T, Vetrugno L, De Monte A. Evaluation of Drug Wastage in the Operating Rooms and Intensive Care Units of a Regional Health Service. Anesth Analg. 2021 May 1;132(5):1450-1456.
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